Jesus’ first victory was over his most powerful foes—Satan and the demons. Expelling them from heaven, he hurled them down to the earth.
Knowing that their time is short, these wicked spirits have vented their violent anger on mankind, causing great woe.
This woe is symbolized in Revelation by the ride of three more horsemen. (Revelation 6:3-8; 12:7-12) In line with Jesus’ prophecy concerning “the sign of [his] presence and of the conclusion of the system of things,” their ride has resulted in warfare, famine, and deadly plague. (Matthew 24:3, 7; Luke 21:7-11)
Like literal birth pangs, these “pangs of distress” will no doubt continue to intensify until Christ ‘completes his conquest’ by destroying every vestige of Satan’s visible organization.*—Matthew 24:8.
http://wol.jw.org/en/wol/d/r1/lp-e/2005044?q=horsemen+of+revelation&p=par

The Russian Defense Ministry says the US missile strike on a Syrian airfield wasn't very effective, with only 23 out of 59 Tomahawk missiles reaching their target. The locations of the remaining 36 missiles’ impact is now unknown, the ministry added.