Jump to content
The World News Media

Investigadores españoles identifican alteraciones cerebrales que permiten la detección precoz del alzhéimer


Raquel Segovia

Recommended Posts

  • Member

El descubrimiento abre la vía a ensayos clínicos para prevenir esta demencia en personas sin síntomas pero con una carga genética que aumenta el riesgo de padecerla

Investigadores españoles de la Fundación Pascual Maragall han realizado un descubrimiento pionero a nivel internacional que permitirá la detección precoz de algunos tipos de la enfermedad de Alzheimer en personas aún sanas y sin síntomas. Esta dolencia, que es el forma más común de demencia, en España afecta a unas 800.000 personas, un volumen de enfermos que podría triplicarse en los próximos 30 años hasta adquirir rasgos de epidemia.

Los expertos españoles, apoyados económicamente por la Fundación La Caixa, publicarán hoy los resultados del mayor estudio mundial de neuroimagen -resonancias magnéticas cerebrales- realizado con personas sanas, pero portadoras del gen que confiere el mayor riesgo de sufrir alzhéimer, el APOE-E4. En este trabajo, que publicará la revista ciéntifica ‘Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association’, han participado 533 personas de 45 a 76 años, de las que 272 eran portadoras del gen APOE-E4, pertenecientes a un proyecto más global, el Estudio Alfa, que con 2.743 voluntarios investiga desde la fundación catalana sobre diferentes aspectos de la enfermedad.

La investigación, dirigida por los doctores José Luis Molinuevo y Juan Domingo Gisbert, ha permitido identificar mediante la comparación de las resonancias diferencias neuroanatómicas significativas -alteraciones de la estructura cerebral- proporcionales a la carga genética asociada al riesgo de alzhéimer en los participantes. Unas alteraciones vinculadas a la carga del APOE-E4 que son más evidentes a partir de los 60 años, que es la misma edad a la que se producen otras alteraciones cerebrales vinculadas a la enfermedad.

Este hallazgo, según valoraron los expertos españoles, representa un paso al frente en la prevención de la enfermedad, ya que permitirá tener en cuenta las alteraciones identificadas en el diseño de ensayos clínicos dirigidos a prevenir el alzhéimer mucho antes de que aparezcan los síntomas clínicos. «Conocer el rol y los cambios estructurales provocados por los diferentes factores de riesgo nos permitirá diseñar mejores ensayos clínicos», explicó José Luis Molinuevo. «La investigación es la única vía para avanzar en la identificación precoz y la prevención de esta enfermedad, que puede convertirse en una pandemia del siglo XXI», según añadió Ángel Font, director corporativo de Investigación y Estrategia de la Fundación La Caixa.

La detección precoz y la prevención de hecho son los instrumentos fundamentales de los especialistas en la lucha contra el alzhéimer porque esta enfermedad neurodegenerativa, que afecta a un 10% de los mayores de 65 años y que representa entre el 60% y el 80% de las demencias diagnosticadas en el mundo, todavía no tiene cura. El hecho de conocer algunos de los marcadores que permiten anticipar que una persona sana tiene alto riesgo de desarrollar la dolencia es clave para una intervención temprana, porque los principales síntomas que delatan el padecimiento de la patología -pérdida de memoria severa, desorientación o problemas del habla y la escritura- no se manifiestan hasta años después del inicio de su desarrollo.

 

Link to comment
Share on other sites


  • Views 170
  • Replies 0
  • Created
  • Last Reply

Top Posters In This Topic

Popular Days

Top Posters In This Topic





  • Recently Browsing

    • No registered users viewing this page.
  • Popular Contributors

  • Topics

  • Posts

    • It appears to me that this is a key aspect of the 2030 initiative ideology. While the Rothschilds were indeed influential individuals who were able to sway governments, much like present-day billionaires, the true impetus for change stems from the omnipotent forces (Satan) shaping our world. In this case, there is a false God of this world. However, what drives action within a political framework? Power! What is unfolding before our eyes in today's world? The relentless struggle for power. The overwhelming tide of people rising. We cannot underestimate the direct and sinister influence of Satan in all of this. However, it is up to individuals to decide how they choose to worship God. Satanism, as a form of religion, cannot be regarded as a true religion. Consequently, just as ancient practices of child sacrifice had a place in God's world, such sacrifices would never be accepted by the True God of our universe. Despite the promising 2030 initiative for those involved, it is unfortunately disintegrating due to the actions of certain individuals in positions of authority. A recent incident serves as a glaring example, involving a conflict between peaceful Muslims and a Jewish representative that unfolded just this week. https://www.theguardian.com/world/2024/mar/11/us-delegation-saudi-arabia-kippah?ref=upstract.com Saudi Arabia was among the countries that agreed to the initiative signed by approximately 179 nations in or around 1994. However, this initiative is now being undermined by the devil himself, who is sowing discord among the delegates due to the ongoing Jewish-Hamas (Palestine) conflict. Fostering antisemitism. What kind of sacrifice does Satan accept with the death of babies and children in places like Gaza, Ukraine, and other conflicts around the world, whether in the past or present, that God wouldn't? Whatever personal experiences we may have had with well-known individuals, true Christians understand that current events were foretold long ago, and nothing can prevent them from unfolding. What we are witnessing is the result of Satan's wrath upon humanity, as was predicted. A true religion will not involve itself in the politics of this world, as it is aware of the many detrimental factors associated with such engagement. It understands the true intentions of Satan for this world and wisely chooses to stay unaffected by them.
    • This idea that Satan can put Jews in power implies that God doesn't want Jews in power. But that would also imply that God only wants "Christians" including Hitler, Biden, Pol Pot, Chiang Kai-Shek, etc. 
    • @Mic Drop, I don't buy it. I watched the movie. It has all the hallmarks of the anti-semitic tropes that began to rise precipitously on social media during the last few years - pre-current-Gaza-war. And it has similarities to the same anti-semitic tropes that began to rise in Europe in the 900's to 1100's. It was back in the 500s AD/CE that many Khazars failed to take or keep land they fought for around what's now Ukraine and southern Russia. Khazars with a view to regaining power were still being driven out into the 900's. And therefore they migrated to what's now called Eastern Europe. It's also true that many of their groups converted to Judaism after settling in Eastern Europe. It's possibly also true that they could be hired as mercenaries even after their own designs on empire had dwindled.  But I think the film takes advantage of the fact that so few historical records have ever been considered reliable by the West when it comes to these regions. So it's easy to fill the vacuum with some very old antisemitic claims, fables, rumors, etc..  The mention of Eisenhower in the movie was kind of a giveaway, too. It's like, Oh NO! The United States had a Jew in power once. How on earth could THAT have happened? Could it be . . . SATAN??" Trying to tie a connection back to Babylonian Child Sacrifice Black Magick, Secret Satanism, and Baal worship has long been a trope for those who need to think that no Jews like the Rothschilds and Eisenhowers (????) etc would not have been able to get into power in otherwise "Christian" nations without help from Satan.    Does child sacrifice actually work to gain power?? Does drinking blood? Does pedophilia??? (also mentioned in the movie) Yes, it's an evil world and many people have evil ideologies based on greed and lust and ego. But how exactly does child sacrifice or pedophilia or drinking blood produce a more powerful nation or cabal of some kind? To me that's a giveaway that the authors know that the appeal will be to people who don't really care about actual historical evidence. Also, the author(s) of the video proved that they have not done much homework, but are just trying to fill that supposed knowledge gap by grasping at old paranoid and prejudicial premises. (BTW, my mother and grandmother, in 1941 and 1942, sat next to Dwight Eisenhower's mother at an assembly of Jehovah's Witnesses. The Eisenhower family had been involved in a couple of "Christian" religions and a couple of them associated with IBSA and JWs for many years.)
  • Members

  • Recent Status Updates

  • Forum Statistics

    • Total Topics
      65.4k
    • Total Posts
      158.9k
  • Member Statistics

    • Total Members
      17,669
    • Most Online
      1,592

    Newest Member
    Miracle Pete
    Joined
×
×
  • Create New...

Important Information

Terms of Service Confirmation Terms of Use Privacy Policy Guidelines We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.