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A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain. The field of cannabis research is vast and diverse. From biochemical studies of the plant itself to physiological and chemical studies of its pharmacology to psychological and social research into its effects, researchers studying cannabis produce the knowledge at the foundation of industry innovation and public policy. Yet perhaps the most important research being done in this new era of expanded access to legal cannabis pertains to just one facet of the plant: the humble cannabinoid. Cannabinoids, the chemicals that qualify the plant as a drug, are the sine qua non of the commercial and medical significance of cannabis.