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Found 3 results

  1. via .ORGWorld News
  2. Un grupo de científicos publicó una investigación en la que se detallan dos tipos de vacunas que combatirán la enfermedad y que podrán ser usados a partir del año 2018. Los efectos en los pacientes de los ensayos clínicos Dos vacunas experimentales contra el virus del ébola demostraron ser una promesa para proteger en menos de un año contra la fiebre hemorrágica, de acuerdo con los resultados de un amplio ensayo clínico publicado el miércoles. El reporte en el New England Journal of Medicine hace el primer recuento completo de un esfuerzo a gran escala para probar lo que podría ser la primera vacuna contra el ébola. El brote del virus altamente contagioso y frecuentemente mortal dejo más de 11.000 fallecidos, principalmente en Liberia, Guinea y Sierra Leona cuando afectó al oeste de África desde finales de 2013 hasta 2016. El brote mortal dejo más de 11.000 fallecidos (iStock) La fase II del estudio involucró a 1.500 personas en Monrovia, Liberia. Los participantes fueron elegidos al azar para recibir una o dos vacunas para ser probadas o un placebo. La primera vacuna candidata fue el precursor rVSV-ZEBOV, inicialmente diseñado por científicos del gobierno de Canadá y ahora autorizado a Merck, Sharp y Dohme Corporation. La segunda vacuna fue cAd3-EBOZ, desarrollada en conjunto por el instituto nacional para alergias y enfermedades infecciosas de Estados Unidos (NIAID) y GlaxoSmithKline Después de un mes, 84% de los que recibieron el rVSV-ZEBOV desarrollaron un anticuerpo. El 80% siguieron estando protegidos durante un año. El nuevo brote de ébola surgió en el Congo, de donde es originaria la enfermedad (OMS) En el caso de la otra vacuna candidata, cAd3-EBOZ, el 71% desarrolló una respuesta de anticuerpo, y 64% siguió teniendo la misma respuesta en un año, cuando el tratamiento terminó. "Este tratamiento clínico ha aportado valiosa información que es esencial para continuar el desarrollo de estas dos vacunas candidatas y que también han demostrado que una investigación bien diseñada, éticamente sólida, se puede diseñar durante una epidemia", dijo Anthony Fauci, director de NIAID. "Una vacuna segura y efectiva sería un complemento importante a las clásicas medidas de seguridad pública para controlar un inevitable brote de ébola", añadió. A partir del 2018, las vacunas estarán disponibles (Shutterstock) Algunas personas que recibieron las vacunas experimentaron "de leves a moderados efectos que se resuelven, tales como dolor de cabeza, dolor muscular, estado febril y fatiga", dijo el reporte. "Sobre todo, los investigadores dijeron que no se identificaron mayores preocupaciones de seguridad relacionadas con las vacunas. La mayoría de los asuntos médicos serios reportados durante el proceso fueron debido a la malaria". La prueba fue conducida como parte de una colaboración de investigación clínica entre Estados Unidos y Liberia, conocida como Partnership for Research on Ebola Virus in Liberia (PREVAIL). Unos 15 tipos de vacunas están siendo diseñadas en el mundo para prevenir esta enfermedad. Los expertos han dicho que las primeras vacunas podrían ser aprobadas para usarse en 2018, utilizando un proceso regulatorio expedito. Con información AFP
  3. The patient who was recently admitted and isolated at Lacor hospital in Gulu district, after profuse bleeding, is suffering from a bleeding disorder, medical personnel have announced. Dr Cyprian Opira, the executive director of the hospital says preliminary tests conducted on the patient indicate that she is suffering from lack of blood clotting factors, a condition that occurs when blood cannot clot properly. The patient was isolated over the weekend after being transferred from Adjumani district with complaints of bleeding from her body openings. Dr Opira says the hospital had a very difficult time managing the bleeding after the patient rejected blood transfusion on religious grounds. The patient is a follower of Jehovah's Witness, a religious group that bars its members from undertaking blood transfusions, donating or storing their own blood for transfusion. Jehovah's Witnesses' literature teaches that rejecting transfusions is an indisputable religious stand and that those who respect life as a gift from God do not try to sustain life by taking in blood, even in an emergency. To them accepting transfusion is regarded as abandoning religious doctrines. However, Dr Opira says that the bleeding has now subsided as the hospital waits for Ebola test results on samples taken to Uganda Virus Research Institute in Entebbe. He called for calm adding that health workers are well prepared to handle any emergency. The Ebola fear came barely a month after the World Health Organisation-WHO confirmed an outbreak of Ebola in the Democratic Republic of Congo. According to the DRC health ministry, three people had died after testing positive to the virus in the remote Likati health district. Ebola is a rare but deadly virus that causes bleeding inside and outside the body. It spreads through contact with the skin or bodily fluids of an infected animal or person. Medical experts say that the virus wrecks the immune system and damages almost every organ. To date, the disease has no cure. The last outbreak killed more than 11,000 when the virus swept through the West African states of Liberia, Guinea and Sierra Leone Last year. It remains the most severe outbreak of Ebola since the discovery of Ebola viruses in 1976. Uganda has witnessed five Ebola outbreaks over the past 14 years which have been quickly contained through a combination of epidemiological luck and a well-coordinated response system operating at several levels of the health service. The most devastating was the first Ebola outbreak in Gulu in 2000 which infected 425 people and killed 224. URN http://allafrica.com/stories/201706060436.html
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