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  1. According to the Telegraph, the World Health Organization will change its definition of disabilities to classify people without a sexual partner as “infertile.” The controversial new classifications will make it so that heterosexual single men and women, as well as gay men and women who are seeking in vitro fertilization to have a child, will receive the same priority as couples. This could make access to public funds for IVF available to all. The move to extend the definition of a disability to include social conditions has, predictably, angered some who consider it overreach by a medical organization that sets global standards. Josephine Quintavalle, a pro-life activist and director of Comment on Reproductive Ethics told the Telegraph, “This absurd nonsense is not simply re-defining infertility but completely side-lining the biological process and significance of natural intercourse between a man and a woman.” The “natural intercourse” intercourse line is painful but expected. Quantaville took it a step further down the anti-science road by saying, “How long before babies are created and grown on request completely in the lab?” For the WHO’s Dr. David Adamson, one of the authors of the new standards, this move is about creating medical equality. He says, “The definition of infertility is now written in such a way that it includes the rights of all individuals to have a family, and that includes single men, single women, gay men, gay women.” Dr. Adamson adds that, “It puts a stake in the ground and says an individual’s got a right to reproduce whether or not they have a partner.” For countries with government provided healthcare and public funding for IVF procedures, this could have significant ramifications. “It fundamentally alters who should be included in this group and who should have access to healthcare. It sets an international legal standard. Countries are bound by it,” Adamson says. Under the American Disabilities Act, a person with a disability is defined as someone with “a physical or mental impairment that substantially limits one or more major life activities, a person who has a history or record of such an impairment, or a person who is perceived by others as having such an impairment.” Because the ADA does not name all of the impairments that are covered, the new WHO guidelines could apply, or even be unnecessary. After all, having children is a major life activity for many people. The World Health Organization has still not made its new terms official but they seem to be moving forward. It remains to be seen what effects the move will have on individual countries’ health programs.
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  2. MEXICO CITY, Mexico—While the world awaits a Zika vaccine, the first ever injection against dengue fever is spreading, with Mexico becoming next week the latest country where people can get the shot. French pharmaceutical giant Sanofi is presenting its Dengvaxia vaccine to doctors at an event in eastern Mexico on Saturday, while people aged nine to 45 will be able to get the shot from their physicians from Monday. After public programs were launched in the Philippines and Brazil’s state of Parana this year, the company is rolling out the vaccine in the private sector in Mexico while health authorities prepare a public immunization plan. The head of Sanofi’s dengue program, Guillaume Leroy, told Agence France-Presse in Mexico City that the company already has one million doses ready in the country. Leroy said it was difficult to estimate how much the vaccine will cost in Mexico as it will depend on the distribution networks and the public vaccination program. The mosquito-borne virus costs governments around the world $18 billion a year, Leroy said. “We estimate that in Mexico and in other countries that the benefits will outweigh the costs of the (vaccine) intervention,” he said. The company will have a “fair policy throughout the world and affordable for health authorities.” Zika vaccine Mexico was the first country in the world to give regulatory approval to the vaccine in December last year. Seven others followed suit, including Brazil, Costa Rica, El Salvador, Guatemala, Paraguay, Peru and the Philippines. Sanofi is awaiting authorizations in 18 other countries. The fast-growing disease infects as many as 400 million people every year, according to the World Health Organization (WHO), which has endorsed the vaccine. Sanofi’s research and development work took 20 years, costing more than 1.5 billion euros ($1.7 billion). Now, Sanofi and other pharmaceutical firms are racing to find a weapon against Zika, which like dengue is carried by the Aedes aegypti mosquito. “Developing a vaccine against Zika will be easier after developing a vaccine against dengue,” Leroy said, noting that the viruses share genetic similarities. “All these investments (on dengue) through more than 100 collaborations worldwide allow us today to gain a lot of time on different vaccinal approaches” against Zika, he said. Some 70 countries and territories have reported local mosquito-borne Zika transmission, with Brazil by far the hardest hit and the WHO declaring it a public health emergency. Zika causes only mild symptoms for most people such as fever and a rash, but infected pregnant women can give birth to babies with microcephaly, a deformation marked by abnormally small brains and heads. – Vaccine concerns – Scientists had also long been stumped by dengue, which has four separate strains, forcing researchers to find a drug able to fight all of them at once. Dengue can trigger a crippling fever, along with muscle and joint pain. But clinical tests on 40,000 people from 15 countries found Dengvaxia can immunize two thirds of people aged nine years and older, rising to 93 percent for the more severe form of the disease, dengue hemorrhagic fever. It was also found to reduce the risk of hospitalization by 80 percent. Brazil launched a public immunization program for 500,000 people in Parana in August, while the Philippines has injected 489,000 public school children aged nine since it became in April the first country to use the vaccine. Philippines health department spokesman Eric Tayag said authorities followed WHO recommendations, which say it should not be given to children under nine years old. “We are tracking each child” to look for any sign of dengue or side effects, Tayag said. Some scientists have voiced concerns about studies showing that the vaccine could give dengue to people who have never had the virus. Scott Halstead, founder of the Pediatric Dengue Vaccine Initiative, told AFP that the WHO was “being hasty” in recommending the vaccine and that people should be tested to see if they have had dengue before being vaccinated. “It’s not ethical to give a vaccine that harms someone,” Halstead said. But Leroy noted that Dengvaxia, in addition to the WHO’s green light, is getting approval from government health regulators. “It is a great solution and the first solution because dengue did not have until now any specific medial solution to treat this illness,” Leroy said, adding that Sanofi is conducting studies in Asia among younger people to see if the vaccine’s reach can expand.
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