By Health and Medicine
"A pack a day keeps lung cancer away" quoted Dr Ian McDonald prominent cancer surgeon. Dr Henry Garland said it was a "harmless pastime". Both men were enlisted by the FDA to do tests on Laetrile (B17) stating "No satisfactory evidence has been produced to indicate any significant cytotoxic effect of Laetrile on the cancer cell". Dr Ian McDonald died when his cigarette set his bed on fire, Dr Garland died of lung cancer.
By Guest Indiana
Orlando, Fla. (April 6, 2019) - Findings from a new study show that the compound responsible for chili peppers' heat could help slow the spread of lung cancer, the leading cause of cancer death for both men and women. Most cancer-related deaths occur when cancer spreads to distant sites, a process called metastasis.
"Lung cancer and other cancers commonly metastasize to secondary locations like the brain, liver or bone, making them difficult to treat," said Jamie Friedman, a doctoral candidate who performed the research in the laboratory of Piyali Dasgupta, PhD, at Marshall University Joan C. Edwards School of Medicine. "Our study suggests that the natural compound capsaicin from chili peppers could represent a novel therapy to combat metastasis in lung cancer patients."
Friedman will present the research at the American Society for Investigative Pathology annual meeting during the 2019 Experimental Biology meeting to be held April 6-9 in Orlando, Fla.
In experiments involving three lines of cultured human non-small cell lung cancer cells, the researchers observed that capsaicin inhibited invasion, the first step of the metastatic process. They also found that mice with metastatic cancer that consumed capsaicin showed smaller areas of metastatic cancer cells in the lung compared to mice not receiving the treatment.
Additional experiments revealed that capsaicin suppresses lung cancer metastasis by inhibiting activation of the protein Src. This protein plays a role in the signaling that controls cellular processes such as proliferation, differentiation, motility and adhesion.
"We hope that one day capsaicin can be used in combination with other chemotherapeutics to treat a variety of lung cancers," said Friedman. "However, using capsaicin clinically will require overcoming its unpleasant side effects, which include gastrointestinal irritation, stomach cramps and a burning sensation."
Hello guest! Please register or sign in (it's free) to view the hidden content.
Johnson & Johnson ganó una apelación contra una mujer con cáncer que exigía USD 72 millones y culpaba al talco para bebésBy Raquel Segovia
La Corte de Apelaciones del Distrito Este de Missouri falló a favor del gigante farmacÃ©utico y de productos de higiene dado a una decisiÃ³n reciente de la Corte Suprema de Justicia que limitÃ³ el lugar donde se podÃan presentar demandas por lesiones
El gigante farmacÃ©utico y de productos de higieneÂ Johnson & Johnson (J&J)Â ganÃ³ el martes la apelaciÃ³n a un veredicto deÂ USD 72 millonesÂ a favor de la familia de una mujer cuya muerte, afirmaban, se debÃa al uso de los productos de la compaÃ±Ãa basados en talco.
Â Play La Corte de Apelaciones del Distrito Este de Missouri dijo queÂ dada una decisiÃ³n reciente de la Corte Suprema de los Estados Unidos, que limitÃ³ el lugar donde se podÃanÂ presentar demandas por lesiones, el caso sobre la muerte deÂ Jacqueline Fox, residente de Alabama, no deberÃa haber sido juzgado en San Luis.
En febrero de 2016, la familia de Fox fue la primera beneficiada de cuatro sentencias de la corte estatal de San Luis que sumaron un costo total de USD 307 millones en reparaciones que J&J debÃa pagar a sus demandantes.
Â La compaÃ±Ãa advirtiÃ³ queÂ aÃºn enfrenta 4.800 casos de demandantesÂ a nivel nacional con reclamos semejantes. Si bien muchos de esos casos estÃ¡n en Missouri, donde la Justicia fallÃ³ a favor suyo, muchos otros estÃ¡n en California, dondeÂ
Hello guest! Please register or sign in (it's free) to view the hidden content. . Â Eva Echeverria ganÃ³ USD 417 millones en un juicio contra J&J en Los Ãngeles (AP) En junio, la Corte Suprema de Estados Unidos, en una decisiÃ³n a un caso que involucrÃ³ aÂ Bristol-Myers Squibb Co., sentenciÃ³ queÂ los tribunales estatalesÂ no podÃan oÃr reclamos de no residentes que no hayan sido lesionados en ese estado en particular o si la compaÃ±Ãa demandada no tenÃa su base en ese estado.
Fox, quiÃ©n muriÃ³ 4 meses previos al juicio, era una de 65 demandantes de las cuales solamente dos eran residentes del estado de Missouri.
Las acciones de J&J, que tambiÃ©n reportaron ganancias mejores de lo esperado en el tercer trimestre, subieronÂ 3,43 % a USD 140.79Â el martes.
A doctor’s poem is going viral in China and raising awareness that smog (surprise!) is a cause of cancerBy Guest Nicole
As toxic clouds of smog continue to cover much of China, more and more Chinese are turning to vent their anger online at the airpocalypse—even turning to poetry.
A poem written by a Chinese chest surgeon has gone viral for pointing out the obvious: there is a link between smog and lung cancer. But in China, where many writers and scholars are punished for speaking out about serious problems, people are hailing the poem as a bold move to raise awareness. Many websites have reproduced the poem in the past week, with the articles racking up thousands of shares and comments on domestic social media (link in Chinese, registration required).
Titled I Long to be King, the verses are told through the viewpoint of a “ground-glass opacity,” the term for a CT scan image showing fluid in the lungs that is an early indicator of lung cancer.
I long to be king,
With my fellows swimming in every vessel.
My people crawl in your organs and body,
Holding the rights for life or death, I tremble with excitement…
From tiny to strong,
From humble to arrogant.
No one cared when I was young,
But all fear me we when full grown.
I’ve been nourished on the delicious mist and haze,
That sweetly warmed my heart,
Always loving when you were heavy drunk and smoking,
Creating me a cozy home.
Dr. Zhao Xiaogang, deputy chief of thoracic surgery at the Shanghai Pulmonary Hospital of Tongji University, said the Chinese public has a low level of understanding about how lung disease develops.
“I see many cancer patients everyday and I feel their pain. I wrote this poem to bring some common knowledge of lung cancer to ordinary people,” he said in an interview by phone. “Lung cancer is the leading form of cancer in China. Stress, smoking and lack of sleep are all factors that can cause cancer, while environmental pollution is also a factor that cannot be ignored.”
The poem originally ran in English in the American medical journal Chest in October. Zhao then allowed the publication of a Chinese translation of the poem in The Paper (link in Chinese), a Chinese state-funded news website, last week. He said he has long enjoyed writing poetry and finds it is a way to express his emotions.
“The intense rise in lung cancer [in China],” Zhao told the Global Times, a state-backed tabloid, “is intimately related to smog.” According to official statistics from 2012, 569,000 people in China die from lung cancer annually. Researchers at the University of California found in 2015 that air pollution kills about 1.6 million people in China each year.
Expatriates and wealthier Chinese commonly use air purifiers at home and wear masks outside to protect themselves, but air purifying machines and effective facemasks are expensive. The poor are also more likely to work outdoors in jobs such as security guards, taxi drivers, and food stall operators.
China may have declared a “war” on pollution and shut down the worst polluting factories, but it is unclear whether the country will ultimately prioritize public health over economic growth. Manufacturing is still the backbone of China’s economy, though the country’s energy agency said last week it plans to invest 2.5 trillion yuan ($361 billion) into renewable power generation by 2020 in a bid to reduce reliance on burning coal.
However, authorities have sent mixed signals about whether it condones open discussion about pollution. State-run media outlets regularly air in-depth stories about pollution, but they tend to highlight steps the government is taking rather than investigate short-term or long-term health effects. Some Chinese artists have had leeway to protest against the smog, but online comments from citizens criticizing the government’s handling of the crisis have been swiftly removed. Last year, censors pulled an independent journalist’s blistering anti-pollution documentary, Under the Dome, from websites after it racked up hundreds of millions of views.
So it is unsurprising that Zhao was careful to stress that environmental factors are not the only causes of lung cancer. There are many things people can do to lower their risk, such as exercising, eating plenty of fruit and vegetables, avoiding cigarette smoke, and managing stress, he said.
As for the toxic air? “Wearing masks helps of course, but it is best to avoid pollution altogether,” said Zhao. “But just as the haze in Los Angeles was solved eventually, I have faith that the Chinese government will tackle the serious pollution and that it won’t take too long.”
Hello guest! Please register or sign in (it's free) to view the hidden content.