Jump to content
The World News Media

Scientists add ‘Disease X’ to list of potential future pandemics amid warning the next killer...


TheWorldNewsOrg
 Share

Recommended Posts


  • Views 313
  • Replies 1
  • Created
  • Last Reply

Top Posters In This Topic

Top Posters In This Topic

List of Blueprint priority diseases

2018 annual review of the Blueprint list of priority diseases

For the purposes of the R&D Blueprint, WHO has developed a special tool for determining which diseases and pathogens to prioritize for research and development in public health emergency contexts. This tool seeks to identify those diseases that pose a public health risk because of their epidemic potential and for which there are no, or insufficient, countermeasures. The diseases identified through this process are the focus of the work of R& D Blueprint. This is not an exhaustive list, nor does it indicate the most likely causes of the next epidemic. 

The first list of prioritized diseases was released in December 2015.

Using a published prioritization methodology, the list was first reviewed in  January 2017.

February 2018 - Second annual review

Report of the meeting pdf, 460kb

The second annual review occurred 6-7 February, 2018. Experts consider that given their potential to cause a public health emergency and the absence of efficacious drugs and/or vaccines, there is an urgent need for accelerated research and development for*:

  • Crimean-Congo haemorrhagic fever (CCHF)
  • Ebola virus disease and Marburg virus disease
  • Lassa fever
  • Middle East respiratory syndrome coronavirus (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS)
  • Nipah and henipaviral diseases
  • Rift Valley fever (RVF)
  • Zika
  • Disease X

Disease X represents the knowledge that a serious international epidemic could be caused by a pathogen currently unknown to cause human disease, and so the R&D Blueprint explicitly seeks to enable cross-cutting R&D preparedness that is also relevant for an unknown “Disease X” as far as possible.

A number of additional diseases were discussed and considered for inclusion in the priority list, including: Arenaviral hemorrhagic fevers other than Lassa Fever; Chikungunya; highly pathogenic coronaviral diseases other than MERS and SARS; emergent non-polio enteroviruses (including EV71, D68); and Severe Fever with Thrombocytopenia Syndrome (SFTS).

These diseases pose major public health risks and further research and development is needed, including surveillance and diagnostics. They should be watched carefully and considered again at the next annual review. Efforts in the interim to understand and mitigate them are encouraged.

Although not included on the list of diseases to be considered at the meeting, monkeypox and leptospirosis were discussed and experts stressed the risks they pose to public health. There was agreement on the need for: rapid evaluation of available potential countermeasures; the establishment of more comprehensive surveillance and diagnostics; and accelerated research and development and public health action.

Several diseases were determined to be outside of the current scope of the Blueprint: dengue, yellow fever, HIV/AIDs, tuberculosis, malaria, influenza causing severe human disease, smallpox, cholera, leishmaniasis, West Nile Virus and plague. These diseases continue to pose major public health problems and further research and development is needed through existing major disease control initiatives, extensive R&D pipelines, existing funding streams, or established regulatory pathways for improved interventions. In particular, experts recognized the need for improved diagnostics and vaccines for pneumonic plague and additional support for more effective therapeutics against leishmaniasis.

The experts also noted that:

For many of the diseases discussed, as well as many other diseases with the potential to cause a public health emergency, there is a need for better diagnostics. 

Existing drugs and vaccines need further improvement for several of the diseases considered but not included in the priority list.

Any type of pathogen could be prioritised under the Blueprint, not only viruses.

Necessary research includes basic/fundamental and characterization research as well as epidemiological, entomological or multidisciplinary studies, or further elucidation of transmission routes, as well as social science research.

There is a need to assess the value, where possible, of developing countermeasures for multiple diseases or for families of pathogens.

The impact of environmental issues on diseases with the potential to cause public health emergencies was discussed. This may need to be considered as part of future reviews.

The importance of the diseases discussed was considered for special populations, such as refugees, internally displaced populations, and victims of disasters.

The value of a One Health approach was stressed, including a parallel prioritization processes for animal health. Such an effort would support research and development to prevent and control animal diseases minimising spill-over and enhancing food security. The possible utility of animal vaccines for preventing public health emergencies was also noted.

Also there are concerted efforts to address anti-microbial resistance through specific international initiatives. The possibility was not excluded that, in the future, a resistant pathogen might emerge and appropriately be prioritized. 

*The order of diseases on this list does not denote any ranking of priority.

http://www.who.int/blueprint/priority-diseases/en/

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...
 Share





  • Recently Browsing

    • No registered users viewing this page.
  • Popular Contributors

  • Topics

  • Posts

    • Watchtowerarchive.com We offer over 1000 books, over 200 photos and many other historical writings as well as Biblical Museum artifacts and many original items that are related to the Watchtower Bible and Tract Society and Jehovah's Witnesses. We have had happy and satisfied customers from every corner of the earth including countries under ban or restrictions as well as many Bethel Branches and members at World Headquarters of Jehovah's Witnesses. Feel free to browse our selections and ask any questions. WatchtowerArchive is a Star seller on Etsy with 100% positive feedback on eBay, and have been a seller for over 20 years.   Welcome to our bookstore: "Watchtower Historical Bibles/Items and Research Publications" on watchtowerarchive.com    Since the "Proclaimers" book came out in 1995 the desire to acquire Watchtower memorabilia and have a personal library or museum of Watchtower items has grown. The Watchtower Society itself now has an archive department known as "Writing Archives" which was established by the Writing Committee of the Governing Body to preserve our rich theocratic history. Many of the hundreds of items we offer on eBay, Etsy and watchtowerarchive are reproductions from the original items which have been donated to the archive department.     We offer hundreds of historical Bibles both original and as facsimiles such as the Gutenberg Bible, Tyndale and about 250  others. We also offer many original Bible leafs that are also hundreds of years old. We offer many museum replicas and facsimiles of Biblical artifacts and many other things of interest to Jehovah's Witnesses and others interested in Biblical historical artifacts such as those related to the Divine Name "Jehovah" going back thousands of years. We also have many of the books quoted by the Watchtower Society and hundreds of photos and reproductions of hundreds of Watchtower memorabilia from the 19th to early 20th Centuries such as the Photo-Drama of Creation items. We have items such as the Dead Sea Scrolls now on display in the Bible History exhibit as mentioned at the 2013 Annual Meeting. Many people are interested in copying to the best of their ability the Bethel Library including the thousands of books referred to and quoted from in the many publications of the Watchtower Society for research. We have books dealing with the following topics: Hundreds of Bible Translations, Biblical Reference Books, Early Christianity, History, Science, Pagan Origins, Archaeology, Jehovah's Witnesses, Holocaust, books related to prophecy about 1914, books by or about Jehovah's Witnesses, Blood transfusion alternatives, religious terrorism and many other subjects. Also we offer at a large discount genuine forever stamps on the website watchtowerarchive.com with no sales tax and free shipping to help our friends with letter writing.    According to our Scriptural conscience and Biblical principle to receive free and give free  no recent new publications are ever sold which you may get for free at a Kingdom Hall. Any profits are donated to the World wide work of Jehovah's Witnesses.                                                                                                                                                              Sincerely, Bruce Quimby
    • It is my personal opinion, for what it’s worth, that things like polio, and monkey pox, and other viruses are spontaneously created from sewage with all that sloshing around, etc. If you don’t eat or drink sewage you’ll be relatively safe if you stay away from people that do.
    • Polio is circulating in NYC. New York City health officials said that the virus was detected in the city’s sewage system, which implies that it’s circulating in the local area. They urged people who aren’t yet vaccinated against the virus—which can cause permanent paralysis of the limbs and in some cases, death—to get their shots. The discovery of polio in NYC comes after the first identified polio case in the US in years: an unvaccinated adult in Rockland County, NY, last month.
    • CO2 is ……… Plant Food! That’s where trees get the carbon to make wood!
    • CTRL - Shift -X when in VS Code, and paste the line below into the search box. DavidAnson.vscode-markdownlint shd101wyy.markdown-preview-enhanced qufiwefefwoyn.inline-sql-syntax ms-vscode.powershell shinhwagk.mkstring mechatroner.rainbow-csv zh9528.file-size shardulm94.trailing-spaces pizycki.pretty-exception gurumukhi.selected-lines-count
  • Members

  • Recent Status Updates

  • Forum Statistics

    • Total Topics
      64.5k
    • Total Posts
      143.7k
  • Member Statistics

    • Total Members
      17,304
    • Most Online
      1,592

    Newest Member
    cellmell
    Joined
×
×
  • Create New...

Important Information

Terms of Service Confirmation Terms of Use Privacy Policy Guidelines We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.